Contact

Address: 1333, Yunxuan Building, Soochow University

Ren’ai Road 199, Suzhou 215123, China

Email: htke@suda.edu.cn

Education

B. Sc. in Bio-Engineering, 2007, Harbin Institute of Technology

M. Sc. in Biomedical Engineering, 2009, Harbin Institute of Technology

Ph. D. in Biomedical Engineering, 2014, Harbin Institute of Technology

Academic Career

Visiting Scholar, 2012-2013, Depart. of Chemistry, University of Massachusetts Amherst, USA

Assistant/Associate Professor, 2014-present, College of Pharmaceutical Sciences, Soochow University

Teaching Courses

Pharmaceutics, Biopharmaceutics

Honor and Awards

Natural Science Award of Heilongjiang Province (1st Prize), 2014

Excellent Doctoral Dissertation of Harbin Institute of Technology, 2015

Suzhou Higher Education & Research Institutions Leading Talents in Short Supply, 2015

Research Interests

1. Nanomedicine for Tumor Diagnosis and Therapy

2. Multimodal Imaging Probes

3. Theranostic UltrasoundContrast Agents

Selected Publications

1. L Fu, H Ke*. Nanomaterials Incorporated Ultrasound Contrast Agents for Cancer Theranostics. Cancer Biol Med. 2016, 13(3): 313-324.

2. Y Li, Y Deng, X Tian, H Ke*, M Guo, A Zhu, T Yang, Z Guo, Z Ge, X Yang, H Chen*. Multi-Pronged Design of Light-Triggered Nanoparticles to Overcome Cisplatin Resistance for Efficient Ablation of Resistant Tumor. ACS Nano. 2015, 9(10): 9626-9637. (Co-corresponding author*)

3. Y Wang#, T Yang#, H Ke#, A Zhu, Y Wang, J Wang, J Shen, G Liu, C Chen, Y Zhao, H Chen. Smart Albumin-Biomineralized Nanocomposites for MultimodalImaging and Photothermal Tumor Ablation. Adv Mater. 2015, 27(26): 3874-3882. (Co-first author#, featured on Cover)

4. Q Chen, H Ke, Z Dai, Z Liu. Nanoscale Theranostics for Physical Stimulus-Responsive Cancer Therapies. Biomaterials. 2015, 73: 214-230.

5. J Huang, M Guo, H Ke,C Zong, B Ren, G Liu, H Shen, Y Ma, X Wang, H Zhang, Z Deng, H Chen, Z  Zhang. Rational Design and Synthesis of γFe2O3@ Au Magnetic Gold Nanoflowers for Efficient Cancer Theranostics. Adv Mater. 2015, 27(34): 5049-5056.

6. H Ke, X Yue, J Wang, S Xing, Q Zhang, Z Dai, J Tian, S Wang, Y Jin. Gold Nanoshelled Liquid Perfluorocarbon Nanocapsules for Combined Dual Modal Ultrasound/CT Imaging and Photothermal Therapy of Cancer. Small. 2014, 10(6): 1220-1227.

7. H Ke, J Wang, S Tong, Y Jin, S Wang, E Qu, G Bao, Z Dai. Gold Nanoshelled Liquid Perfluorocarbon Magnetic Nanocapsules: A Nanotheranostic Platform for Bimodal Ultrasound/Magnetic Resonance Imaging Guided Photothermal Tumor Ablation. Theranostics. 2014, 4(1): 12-23.

8. H Ke, J Wang, Z Dai, Y Jin, E Qu, Z Xing, C Guo, X Yue, J Liu. Gold Nanoshelled Microcapsules: A TheranosticAgent for Ultrasound Contrast Imaging and Photothermal Therapy. Angew Chem Int Ed. 2011, 50(13): 3017-3021. (Highlighted in Nat Mater and Wiley-VCH)

9. H Ke, J Wang, Z Dai, Y Jin, EQu, Z Xing, C Guo, J Liu, X Yue. Bifunctional Gold Nanorod-Loaded Polymeric Microcapsules for Both Contrast-Enhanced Ultrasound Imaging and Photothermal Therapy. J Mater Chem. 2011, 21(15): 5561-5564.

10. H Ke, Z Xing, B Zhao, J Wang,J Liu, C Guo, X Yue, S Liu, Z Tang, Z Dai. Quantum-Dot-Modified Microbubbles with Bi-Mode Imaging Capabilities. Nanotechnology. 2009, 20(42): 425105. (Featured on Cover)

Books

1. H Ke, H Chen. Chapter 10 - Multimodal Micelles for Theranostic Nanomedicine. Advances in Nanotheranostics II: Cancer Theranostic Nanomedicine. Springer-Verlag, Singapore, 2016.

2. H Ke, X Yue, Z Dai. Chapter 7 - Self-assembled smart hollow microcapsules. Biomimetic Membrane Materials and Technology. Science Press, Beijing, 2010.

Patents

1. H Chen, Y Deng, H Yang, H Ke, L Huang, A Zhu, Z Guo, Preparation and application of multifunctional mesoporous silica nanoparticles for near-infrared photothermal therapy and fluorescence imaging, Chinese Patent, CN201510490341.6

2. H Chen, T Yang, Y Deng, Y Wang, H Ke, Z Guo, H He, H Yang, Y Zou, S Ji, Q Wang, Preparation of copper based human serum albumin nanocomposites for near-infrared photothermal therapy, Chinese Patent, CN201510566206.5

3. Z Dai, H Ke, J Wang, Fabrication of novel theranostic agents based on gold nanoshelled microcapsules, Chinese Patent, ZL201110029229.4

4. Z Dai, H Ke, J Wang, Preparation of theranostic nanomedicine, Chinese Patent, CN201110211436.1

5. Z Dai, H Ke, Z Xing, J Wang, J Liu, S Liu, Novel surfactant based microbubble ultrasound contrast agent, Chinese Patent, CN200810209564.0

6. Z Dai, Z Xing, H Ke, J Wang J Liu, S Liu, Novel polyelectrolyte multilayer coated microbubble ultrasound contrast agent, Chinese Patent, CN200810063911.3

Grants

1. National Natural Science Foundation of China (No. 81871480, 81501585)

2. Natural Science Foundation of Jiangsu Province (No. BK20150348)

3. China Postdoctoral Science Foundation (No. 2015M570475, 2016T90496)

4. Natural Science Foundation of Jiangsu Higher Education Institutions (No. 15KJB310019)