Zhengqing Guo, Ph. D., Assoc. Prof.




College of Radiation Medicine and Protection


Soochow University



Contact

Address: 1313, Building #401, Soochow University

199, Ren’ai Road, Suzhou 215123, China

Email: zqguo@suda.edu.cn


Education

B. Sc. in Chemistry, 2002, Nanchang University

M. Sc. in organic Chemistry, 2005, Xiamen University

Ph. D. in Chemistry, 2010, City University of Hong Kong


Academic Career

Pharmaceutical Researcher, 2005-2006, WuXi Pharma. Tech. Inc. Shanghai.

Research Assistant, 2006-2007, Department of Biology and Chemistry, City University of Hong Kong.

Postdoctoral Fellow, 2010-2013, Department of Biology and Chemistry, City University of Hong Kong.

Associate Professor, 2013-present, College of Radiation Medicine and Protection, Soochow University


Teaching Courses

Basic Chemistry, General Knowledge on Health and Drugs, Nanotechnology and Biomedical Revolution


Honor and Awards

Suzhou Higher Education & Research Institutions Leading Talents in Short Supply, 2015.

Outstanding Academic Performance Award for Research Degree Students, and Research Tuition Scholarship, City University of Hong Kong, 2009.

Excellent Graduate Award, and ‘Wu si-min’ Scholarship, Xiamen University, 2005.


Research Interests

1. Design and synthesis of nanodrugs for photo-therapy.

2. Design of Isotopes-labeled Nanodrugs for Molecular Imaging.


Selected Publications

1. Z Guo#, Y Zou#, H He#, J Rao, S Ji, XCui, H Ke, Y Deng, H Yang, C Chen, Y Zhao, and H Chen*. Bifunctional Platinated Nanoparticles for Photoinduced Tumor Ablation. Adv. Mater. 2016, DOI:10.1002/adma.201602738

2. C Shen, F Yu, W Chu, J Xiang*, P Tan, Y Luo, H Feng, Z Guo*, C Leung*, and T Lau. Synthesis, Structuresand Photophysical Properties of Luminescent Cyanoruthenate(ii) Complexes with Hydroxylated Bipyridine and Phenanthroline Ligands. RSC Advances. 2016, 6(90): 87389-87399.

3. F Yu, C Shen, T Zheng, W Chu, J Xiang*, Y Luo, C Ko, Z Guo*, and T Lau. Acid–Base Behaviourin the Absorption and Emission Spectra of Ruthenium(II) Complexes with Hydroxy-Substituted Bipyridine and Phenanthroline Ligands. Eur. J. Inorg. Chem. 2016, 2016(22): 3641-3648.

4. Z Guo, W-L Tong, and M Chan. Luminescent Oligo(Ethylene Glycol)-functionalized Cyclometalated Platinum(ii) Complexes: Cellular Characterization and Mitochondria-specific Localization. Chem. Commun. 2014, 50(14): 1711-1714.

5. Z Guo, S-M Yiu, and M Chan. Shape-Persistent (Pt-salphen)2 Phosphorescent Coordination Frameworks: Structural Insights and Selective Perturbations. Chem –Eur. J.2013, 19(27): 8937-8947.

6. Z Guo and M Chan. Shape-PersistentBinuclear Cyclometalated Platinum(II) Luminophores: Pushing π-Mediated Excimeric Fluid Emissions into the NIR Region and Ion-Induced Perturbations. Chem –Eur. J.2009, 15(46): 12585-12588.

7. Z Guo, W Tong, and M Chan. Axially Rotating (Pt-salphen)2 Phosphorescent Coordination Frameworks. Chem. Commun. 2009 (41): 6189-6191.

8. P Huang, Z Guo, and Y Ruan. A Versatile Approach for the Asymmetric Syntheses of (1R,9aR)-Epiquinamide and(1R,9aR)-Homopumiliotoxin 223G. Org.Lett. 2006, 8(7): 1435-1438.


Patents

1. Z Guo, H Chen, Y Zou, H He, J Rao. The preparation and application of platinum complex with photodynamic activity in NIR region. CN105198934 A.

2. H Chen, Y Deng, H Yang, H Ke, L Huang, A Zhu, Z Guo. The preparation and application of multifunctional mesoporous silica nanoparticles with NIR photothermal and in-vivo fluorescence imaging characteristics. CN105056233 A.

3. H Chen, T Yang, Y Deng, Y Wang, H Ke, Z Guo, H He, H Yang, Y Zou, S Ji, Q Wang. The preparation and application of copper-based human serum albumin nanocomposite with NIR photothermal characteristics. CN105106958A.

4. P Huang, Z Guo, Y Ruan. A method for total synthesis of epiquinamide with high enantiomeric purity. CN1793144.


Grants

1. National Natural Science Foundation of China (No. 21401136)